WIRELESS ECG & EEG SYSTEMS FOR MICE AND RATS


EPOCH Systems include two sensors; additional sensor transmitters can be ordered individually.

Each channel requires an output cable. To use with BIOPAC MP160/HLT, add one CBL123 per channlel; for BIOPAC MP150/UIM, add one CBL102 per channel.

Sensors are shipped “deactivated” and require the Sensor Activation & Test Utility (EPOCH-ACTI) to start the sensor battery when ready to use the transmitter.

The reusable activator is battery operated and can be used for any deactivated sensors.

Transmitters must be activated within 6 months of shipment to ensure the full 2-month or 6-month active battery-life.

The activator utility can also output two independent channels of data (sinewaves) for testing purposes. When used with an MP Research System, use the power of AcqKnowledge software’s automation and scoring tools to identify seizures, predefine and control recording protocols, or set triggers based on external events (dosing, light changes, etc.).

After recording, use automated EEG analysis routines to quickly score multiple channels of EEG data simultaneously. Derive frequency bands, complete a Frequency analysis, look at Alpha RMS, etc., all with guided automated routines.

Single-Channel ECG Transmitter Implant

The single-channel ECG wireless transmitter implant contains a small amplifier, transmitter, and a battery encapsulated in medical-grade epoxy. Each electrode is 7-strand braided stainless steel with Teflon insulation. Each strand is 50 μm in diameter, making the bare electrode 152 μm in diameter (229 μm diameter insulated). There are two electrode leads on the ECG transmitter; spacing for these leads on the transmitter is detailed below.

Single-channel ECG transmitter electrode spacing schematic looking down at animal’s head. The electrodes exit the bottom of the transmitter toward the animal’s neck and back

Footprint: 8 mm x 9 mm (2 month), 8 mm x 12 mm (6 month)

Weight: 2.3 g (2 month), 4.0 g (6 month)

Volume: 0.756 cm3 (2 month), 1.344 cm3 (6 month)

Output Gain: 2000x; ±1.0 mV range, 1.0 mV in = 2 V out

Bandwidth: 0.1-200 Hz per channel

Input Referred Noise: < 8 μV rms at 100 Hz (11 μV rms at 200 Hz)

System Extensions

Add SleepSign for Animals (SSA100W) for complete sleep data analysis.

Use Camera Systems (CAMSYS4 or CAMSYS8) to monitor and record protocols and animal behavior. Recorded video will be time synchronized to the physiological signals in AcqKnowledge for easy investigation of key areas of interest.

WIRELESS ECG & EEG SYSTEMS FOR MICE AND RATS


2 channels of wireless EEG

Dual-channel implantable EEG/Neural wireless transmitter for pup, mouse, or rat. The wireless transmitter amplifies and transmits two channels of high-fidelity EEG data to an EPOCH System receiver tray for long-term wireless EEG recording from small animals in their home cages.

small implants uniquely suited for neonatal and adult rodent recording

two-week transmitter suitable for pre-weaned rodents (< postnatal day 21)

two-month transmitter suitable for rats as young as postnatal day 7 and older

two-month transmitter suitable for mice as young as postnatal day 12 and older

six-month transmitter suitable for adult rats and mice

transmitter mounts to the skull with cyanoacrylate

reduces surgical time to tens of minutes

Teflon insulated platinum electrode wires are shipped at 10 cm and can be truncated to desired length; custom longer lengths available on request.